Histopathological Correlation of Lipoder Matosclerosis

Abstract

To observe histopathological findings in patients with clinical diagnosis of lipodermatosclerosis. Patients and methods: A total of 5 patients with chronic lipodermatosclerosis were included in the study. All patients were subjected to 1. Complete history taking, 2. General and dermatological examination, 3. Consenting patients were subjected to punch biopsy of the lower limbs. Results: Histopathology of patients with chronic lipodermatosclerosis was studied. Of the 5 cases, 4 showed epidermal atrophy. Increase in pigmentation of basal layer was noted in 3 cases. Dermal changes were observed in 3 cases, showing edematous changes, pseudo-sclerodermatous change and mild septal infiltrates. 2 cases showed extravasation of RBCs. Evidence of lobular panniculitis was noted in 1 case. Conclusion: Histopathological findings of lipodermatosclerosis were consistent with epidermal thinning, increased pigmentation in basal layer, pseudo-scleroderma like changes, extravasation of RBCs and presence of chronic inflammatory infiltrates