A review on hyperlipidemia

Abstract

Hypelipidemia is a condition of elevated lipid level in blood. Hyperlipidemia is a major cause of atherosclerosis and atherosclerosis related conditions like coronary heart disease (CHD), ischemic cerebrovascular disease, peripheral vascular disease and pancreatitis1-2. The increase in lipids like low density lipoproteins (LDL), cholesterol (esters derivatives) and triglycerides are mainly responsible for this condition. These lipids are associated with blood plasma proteins and remain in the dissolved state in the blood. The primary reason for hyperlipidemia is defect in lipid metabolism which is caused by the defect in lipoprotein lipase activity or the absence of the surface Apoprotein C-II. Other causes of hyperlipidemia include various genetic abnormalities and environmental factors.