Investigation on Polyherbal Antipyretic Syrup for Fever

Abstract

Fever is an important and notable sign and symptom of many diseases that are caused in the human body. They are the result of any inflammatory condition, infection or any other disease occur due to any external agents. There are a lot of drugs that are used to control pyrosis in the body. Fever is simply elevation of the body temperature. The chemical constituents isolated from the plants were effective in treating many diseases and were seemed to be potent against all the conditions. Even with the advent of the synthetic drugs, herbal leads have been the drugs of choice in many diseases like CHF, Cancers and more. The plant vitex was extracted using the ethanol water mixture and this extract was used to produce the poly herbal antipyretic syrup. This was investigated on the yeast induced pyrexia and it showed a better activity compared to the standard paracetamol drug and also a marketed formulation. This can be supported by the antioxidant and antibacterial properties of vitex and also supported by the Piper longum that contains piperine which as usually acts as a penetration enhancer in pharmaceutical applications.