Syrup Formulation Incorporating Herbs for the Hepatotoxicity

Abstract

The liver is an important organ in the body that is responsible for the proper metabolism of food and drugs. It eliminates waste material and toxins from food with the help of the enzymes like cytochrome P450. Ficus benghalensis is a very well-known plant that is known for its pharmacological properties like antioxidant, hepatoprotective, immune-boosting, anti-diabetic etc. It also has properties like anti-hypertensive and anti-hyperlipidemic. It was already tested for the hepatoprotective activity, and the extract used was ethanol. Psidium guava is a local plant in tropical countries that are harvested for fruits, and all the plant parts have varied pharmacological activities like anti-diabetic, Anti-inflammatory, anti-hyperlipidemic etc. especially, the leaves of the plant have many significant uses like hepatoprotective which was investigated for the same using methanol extract. The extracts of the Ficus and Guava were incorporated into the syrup formulation, and it was tested for the activity against the hepatotoxicity induced due to the CCl4 and Paracetamol in the albino Wistar rats. The extract and formulation showed a better activity compared to the standard drug.