Effect of Ayurvedic Churnam on the Elevated Blood Sugars by STZ Drug

Abstract

Diabetes Mellitus shortly called as DM is a metabolic disorder which is due to the improper secretion of the insulin by the pancreas. The insensitivity in the reuptake of insulin also causes diabetes. This increases the blood glucose level and affects physiological functions. The majority of the population that is suffering from DM are generally obese or following unhealthy lifestyle habits. There are about half of the world population is suffering from DM and related complications. DM secondary complications include nephropathy, neuropathy, retinopathy and vascular complications like PVD and PAD. Considering the activity of herbs and the safety of the same, an ayurvedic formulation was prepared using herbs, and the same is investigated for the antidiabetic activity. The ayurvedic formulation that is designed in the study is an ayurvedic churnam preparation out of the texts of the Ayurveda books. The polyherbal churnam that is prepared showed a significantly better activity compared to the standard drug and the marketed ayurvedic formulation too. The higher dose of the extract showed higher activity compared to the lower dose of the preparation.