Bio-mimetic synthesis of silver nanoparticles

Abstract

Silver nanoparticles have their demand in various fields of science and technology and their applications extend even in medical and pharmaceutical arenas. They have been used as preservatives, diagnosing aids and potent antibacterial agents. But their production is a serious matter of concern when it comes to cost, efficacy and toxicity issues. Overcoming these limitations green synthesis has taken its advantage for their commercial and large scale synthesis. This research concentrates on the preparation of silver nano particles by using purified leaf extract of Lannea coromandelica and evaluation of the same using UV-Vis Spectrophotometry, FTIR, EDXS, SEM and particle size analysis. The produced nanoparticles exhibited surface plasmon resonance at 420nm in UV spectroscopy. EDS Spectrum showed the presence of metallic silver in the solution. They are roughly cubic in shape, smooth surfaced and measure about 10-20nm in diameter which is evident from the particle size analysis. FTIR studies revealed the presence of O-H groups indicating polyphenols and also confirms capping of proteins over the nanoparticles. The results proved the eco-friendly synthesized silver nanoparticles. The prepared nanoparticles have been analyzed using sophisticated analytical instruments. The results confirm the formation of silver nanoparticles. The bio-mimetic synthesis of silver nanoparticles is relatively safer and cost effective. The potency and effect of silver nanoparticles was determined yet the toxicity was to be considered for establishing it as a therapeutic agent.