Certolizumab-A novel tumour necrosis factor inhibitor for rheumatoid arthritis Mohamed

Abstract

Cytokine play a major role in the development of variety of auto immune disorders like rheumatoid arthiritis. Ex- pression of tumor necrosis factor-α during inflammation has been well established in rheumatoid arthiritis pa- tients. Administration of anti TNF-α factor for rheumatoid arthritis patients inflammation, improve symptoms and retart joint damage. Certolizumab is one of the anti TNF-α agents recently approved for rheumatoid arthritis treatments. In this review we have discussed about various pharmacological aspects of certolizumab related with rheumatoid arthritis.