Review on the Usefulness of Advanced Chromatographic Analytical methods for Determination of Herbal Molecules

Abstract

The pursuit of natural products and herbal medicines has garnered significant attention in recent years due to their potential therapeutic benefits and minimal side effects. To harness the full potential of these traditional remedies, rigorous analytical techniques such as Gas Chromatography-Mass Spectrometry (GC-MS) and High-Performance Liquid Chromatography (HPLC) have emerged as indispensable tools. In this gripping abstract, we present a comprehensive review of studies that have employed GC-MS and HPLC to analyze herbal molecules and essential oils, shedding light on their chemical complexity and pharmacological activities.GC-MS, with its unparalleled capability to identify and quantify volatile and semi-volatile compounds, has been instrumental in the analysis of essential oils. Through its application, an array of bioactive components, including terpenes, phenols, and fatty acids, have been revealed. Studies utilizing HPLC have identified and measured various phytochemicals, including flavonoids, alkaloids, and polyphenols, elucidating their role in conferring medicinal properties to these plant-derived preparations. The validated HPLC methods have become crucial in assessing the stability and safety of pharmaceutical formulations containing herbal compounds, ensuring their efficacy and reliability.As the search for novel therapeutics continues, these cutting-edge analytical techniques will undoubtedly continue to shape the landscape of natural products research, promoting evidence-based herbal medicine practices and advancing the frontiers of modern medicine.