EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF CALOTROPIS GIGANTEAN, TYLOPHORA INDICA AND SARCOSTEMMA SECOMONE

Abstract

The main objective of the present investigation is to evaluate the anti-inflammatory property of Calotropis gigantean, Tylophora indica and Sarcostemma secomone in Wister rats using the Carrageenan induced left hind paw edema. In the study it was observed that the aqueous, ethanol and chloroform extracts were significantly inhibit paw edema induced by carrageenan in rats. The ethanolic extract showed a significant anti-inflammatory property when compared with the aqueous, chloroform, standard and untreated control. Among the three tested plant species S.sarcostemma showed the maximum inhibition in rats.