Development and Validation of RP-HPLC Method for Estimation of Telmisartan in Bulk and Tablet Dosage Form

Abstract

A simple RP-HPLC method in bulk and formulation dosage form for Estimation of Telmisartan has developed. Mobile phase potassium di-hydrogen phosphate and Acetonitrile (60:40) ph adjust with ortho phosphoric acid , C18 sun fire column (250mmx4.6mmx5µm) flow rate 1ml/min, wave length 243 nm, column temperature 45ºc, injection volume10 µl. system suitability parameters of Telmisartan retention time 3.4, plate count 8968, tailing 1.086, % RSD 0.1 those all are within the limit method is suitable for analysis. Validation parameters selectivity, precision, linearity, accuracy, Robustness all are within the limit so method was validated it is use full to pharmaceutical analysis.