Main Article Content

Abstract

Seven 5-ethoxycarbonyl-4-aryl- -6-methyl-3,4-dihydropyrimidinones 4ag are screened for their antibacterial activity against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi and antifungal activity against Candida albicans, Aspergillus flavus, Rhizopus and Mucor. Ciprofloxacin is used for the standard for antibacterial and Amphotericin B is used for the standard for antifungal studies. Compounds 4a, 4b,4c, 4d, 4e and 4f exhibited excellent in vitro antibacterial activity against all the tested organisms. Where as the same set of compounds exerted potent in vitro antifungal activity against Candida albicans, Aspergillus flavus and Rhizopus.

Keywords

Antibacterial activity antifungal activity Dihydropyrimidinones

Article Details

How to Cite
S, C. (2012). ANTIBACTERIAL AND ANTIFUNGAL STUDIES 5-ETHOXYCARBONYL-4-ARYL-6METHYL-3, 4-DIHYDROPYRIMIDINONES . International Research Journal of Pharmaceutical and Applied Sciences, 2(6), 71-73. Retrieved from https://scienztech.org/index.php/irjpas/article/view/365