A TYPICAL REVIEW ON RAPID RESOLUTION LIQUID CHROMATOGRAPHY (RRLC)

Abstract

This review article should focus on the Rapid Resolution Liquid Chromatography (RRLC) has become an increasingly useful approach to achieve higher throughput, improve sensitivity and reduce costs.The potential of high−speed analyses by Rapid Resolution Liquid Chromatography (RRLC) on 1.8 μm porous particles packed into short columns operated at high flow rate was investigated and compared to the performance of 5 μm porous par-ticles packed into conventional colum. In order to display the practicality of RRLC separations, the isocratic analysis of pesticides and the gradient analysis. Often higher temperatures are employed to minimize system back-pressure. With the widespread adoption of RRLC comes the question of HPLC detector compatibility.