EFFECT OF MONOMER ON THE SYNTHESIS OF MOLECULARLY IMPRINTED POLYMERS FOR QUERCETIN

Abstract

In this paper, the effect of change of monomer on the synthesis of molecularly imprinted polymers prepared by bulk polymerization is described. Polymers were prepared under optimized polymerization conditions by changing the monomer using quercetin as a template molecule and EGDMA as a cross linker. The synthesized polymers were characterized by HPLC analysis for their binding capacity for the template and template analogue molecule rutin. The imprinting factor was calculated by calculating the binding capacity of MIPs and NMIPs for the template molecule. It was concluded that the MIPs prepared by using Itaconic acid as a functional monomer are better than acrylamide MIPs