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Abstract
Phallusia arabica is a simple ascidian belonging to the family Ascidiidae. It was extracted successively using different
solvents such as petroleum ether, benzene, methylene chloride, chloroform, ethanol, and water. Screening indicates the presence
of alkaloids, terpenoids, steroids, coumarins, tannins, saponins, flavonoids, quinones, anthroquinone, phenols, aromatic acids,
catechins, proteins, carbohydrates and lipids. Ethanolic extract of Phallusia arabica was subjected to anaesthetic activity by
intracutaneous wheal method. The extract, when administered at a dose of 20 and 40% caused highly significant anaesthetic
activity when compared to the standard drug xylocaine (0.5 & 1%). The mean sleeping time and percentage relaxation of muscle
was also highly significant in the extract treated groups compared to the standard drug, Aminobarbitone.
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