Main Article Content
Abstract
Dacarbazine (DTIC) is widely used as anti-cancer drug and can result in severe cytotoxic effect and sometime this
effect might be fatal. This study was carried to evaluate the effects of the DTIC drug on mice test tissue and some of sperm
parameters. The evaluation of DTIC effects showed that 15 and 20 mg/kg produced significant alteration to some sperm
parameters and the accumulated dose of 10 mg/kg for 3 days caused severe damage to the testis tissue of the treated mice..
Keywords
Dacarbizine
DTIC
Test
Sperms
mice
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How to Cite
Al-Saleh, A. A., & Al-Otaiby, A. M. (2013). Evaluation Effect of Dacarbazine on Mice Testis Tissues and Sperm Parameters. International Research Journal of Pharmaceutical and Applied Sciences, 4(6), 9-13. Retrieved from https://scienztech.org/index.php/irjpas/article/view/749