Investigating the relation between anti-oxidant activity and epileptic enzymes of formulation-40 capsules

Abstract

Seizures and Epilepsy are those major conditions that are common symptoms of many diseases that affect the human nervous system. It is one of the most chronic and commonest of the neurological disorders that is prevalent in almost 5crore people around the world. Even though the drugs are effective and potent, there are various side effects and adverse effects are associated with those drugs. General side effects include the nausea and vomitings, many other specific side effects include altered mental consciousness, confusion anorexia and excessive aggression are also noted in many cases of drugs. In this research, herbal formulations were designed to fight back the free radicals that are generated in the brain and those protective enzyme levels were analyzed to estimate the activity of the formulation in the brain tissue. In the research, the prepared formulation showed a dose dependent activity in restoring the brain protective enzymes and balancing them. The formulation contained herb powders that contain antioxidant chemical constituents which helped for the anti-epileptic formulation. The herbal capsules at dose 500mg/kg showed a better activity compared to the standard drug but without notable side effects and adverse effects.