EFFECT OF ANTIHYPERTENSIVE DRUGS ON AUTONOMIC NERVOUS SYSTEM ACTIVITY

Abstract

The autonomic nervous system is both the monitor and regulator of the 'mileu interieur. ANS regulates the activity of smooth muscle, heart, and glands of GIT, sweat glands adrenal gland and of certain endocrine organs. The assessment of autonomic nervous activity is a frequent and challenging goal of the clinical research. It has been found that hypertension is related to an interaction between the autonomic nervous system and the renin-angiotensin system, together with other factors. Various common antihypertensive drug are used for treating hypertension like Angiotension Converting Enzyme (ACE) inhibitors e.g captopril, enalapril, Angiotension II receptor blockers like losartan, candesartan Beta blockers e.g metoprolol, atenolol, Calcium channel blockers like nifedipine, amlodipine, verapamil. The emphasis is on choosing the drug that best meets each patient need, according to factors such as age, ethnicity and presence of other cardiovascular condition.