STUDY OF LIPID PROFILE AND THE EFFECT OF CARDIAC ENZYMES IN TYPE 2 DIABETES MELLITUS PATIENT DEVELOPING CORONARY HEART DISEASE

Abstract

Dyslipidaemia is frequently present in type 2 diabetes mellitus (T2DM). The predominant features of dyslipidaemia in this disorder include increased flux of free fatty acids (FFA), raised triglyceride (TG) and low high density lipoprotein cholesterol (HDL) levels, a predominance of small, dense (atherogenic) low density lipoprotein cholesterol (LDL) particles and raised apolipoprotein (apo) B values of Posprandial hyperlipidaemia may also be present. Objective: The study was aimed to study lipid profile and the effect of cardiac enzymes in type 2 diabetes mellitus patient developing coronary heart disease. Materials and Methods: From the serum lipid profile, HbA1c, CK-MB and inflammatory markers CRP were analyzed in normal, diabetic subjects without coronary heart diabetic subjects developing coronary heart disease via kit methods.Results and conclusion: Lipid profile, HbA1c, CK-MB and inflammatory markers CRP were significantly increased in type 2 DM subjects developing coronary heart disease as compared to other groups.