CONCEPTS AND SALIENT FEATURES OF ORODISPERSIBLE DRUG DELIVERY SYSTEMS – A REVIEW

Abstract

The development of pharmaceutical technology in past years has presented the development of alternative dosage forms for the patients who have difficulty in swallowing tablets. Fast disintergrating drug delivery system (FDDDS), are the system which disintergrates and releases the active ingredient quickly without the need of water. Among the FDDDSs, the fast disintergrating tablets (FDT) is the more acceptable form of drug delivery system because of its convenience of selfadministration and compactness. The oral route remains the perfect route for the administration of therapeutic agents because of the low cost therapy and ease of administration, which leads to high patient compliance.FDT are tablets, when placed on toungue,disintergrates instantaneously, releasing the drug, which disperses or dissolve in the saliva.FDT have been formulated for pediatric, geriatric, and bedridden patients and for active patients who are busy and traveling and may not have access to water. Fast dissolving tablets are also known as orodispersible, quickdissolve, fast melt, fast dissolve, fast disintegrate, rapid-dissolve, rapid melts or orally dissolve tablets.European pharmacopoeia recently adopted the term “Oro-dispersible tablet” as a tablet to be placed in mouth where it disappears rapidly before swallowing. According to European Pharmacopoeia also, the FDT are the tablets which disintegrate in less than three minutes.This article focuses on classification of Fast Disintergrating Drug Delivery System, the advantages and limitation of Fast Dissolving Tablets.