AMYLASE INHIBITORY ACTIVITY OF COSTUS IGNEUS LEAF EXTRACT

Abstract

Diabetis mlletus is one of the autoimmune diseases where the human population is at the receiving end. The disease affects large human population in the Indian subcontinent. The present study was aimed at inhibiting the enzyme amylase by the methanol leaf extract of Costusigneus. The inhibition assay was performed by Chromogenic DNSA method. The leaf methanol extract has displayed inhibition of 65.48, 35.72 and 3.57% at 500, 250 and 100 µg concentrations. Whereas, the standard Acarbose inhibited the enzyme at all concentrations screened. From the results it indicates that the α-amylase inhibition by the methanol extract of C. igneus is dose dependent